The U.S. Department of Energy (DOE) has announced collaboration agreements with 24 organizations to advance the Genesis Mission, a national initiative aimed at using artificial intelligence (AI) to accelerate scientific discovery, strengthen national security, and promote energy innovation. The announcement follows President Trump’s Executive Order on Removing Barriers to American Leadership in Artificial Intelligence and his America’s AI Action Plan, which seeks to foster innovation, reduce reliance on foreign entities, and enhance the nation’s scientific capabilities.
A meeting at the White House brought together industry representatives along with U.S. Secretary of Energy Chris Wright, DOE Under Secretary for Science and Genesis Mission Director Dr. Darío Gil, and Michael Kratsios, Director of the White House Office of Science and Technology Policy. The event marked the launch of public-private partnerships intended to build scalable national infrastructure for AI-driven research.
“Today’s announcement of 24 new research partnerships is only the beginning, as we deliver on President Trump’s mandate to bring the entire scientific community, including companies, universities, non-profits, and Federal agencies, into the Genesis Mission,” said Assistant to the President and OSTP Director Michael Kratsios. “Harnessing cutting-edge AI for science will dramatically increase the productivity of American scientists and researchers. The Genesis Mission will help America’s scientists automate experiment design, accelerate simulations, and generate predictive models that will lead to breakthroughs in energy, manufacturing, drug discovery, and beyond.”
“Thanks to President Trump’s leadership, the Genesis Mission will be transformative for our country, uniting industry, academia, and our National Labs to deliver powerful and impactful scientific discovery and innovation,” said DOE Under Secretary for Science and Genesis Mission Director Dr. Darío Gil. “These agreements help advance President Trump’s Executive Order to build the national AI platform for scientific discovery and uplift the entire U.S. R&D ecosystem.”
The organizations entering into memorandums of understanding with DOE include technology firms such as Accenture, AMD, Anthropic, Amazon Web Services (AWS), Google, IBM, Intel, Microsoft, NVIDIA as well as other companies involved in computing hardware or AI development like Cerebras Systems and OpenAI.
The DOE stated that these MOUs result from responses to a request for information or ongoing projects related to the Genesis Mission at DOE or its National Laboratories. Any products developed under this mission are intended to be architecture-agnostic.
DOE plans further engagement with private sector collaborators as well as academia and philanthropic organizations in order to expand participation in the Genesis Mission. Requests for Information (RFIs) remain open: “Partnerships for Transformational Artificial Intelligence Models” until January 14th 2026; “Transformational AI Capabilities for National Security” until January 23rd 2026.
For more details about the Genesis Mission or partnership opportunities visit www.genesis.energy.gov.
